Deciphering RNA

The RiboClub brings together ribonucleic acid (RNA) biologists aiming at promoting the study of RNA evolution, structure and function. By fostering regular meetings, exchanging ideas, and sharing infrastructure, the RiboClub creates a unique atmosphere for the recruitment and development of young researchers.

Deciphering RNA

The RiboClub brings together ribonucleic acid (RNA) biologists aiming at promoting the study of RNA evolution, structure and function. By fostering regular meetings, exchanging ideas, and sharing infrastructure, the RiboClub creates a unique atmosphere for the recruitment and development of young researchers.

Latest News

Upcoming seminar

January 13 at 4:30 PM

For more details click here


 

RNA Imaging and Intracellular Dynamics Workshop 

Hosted by the NCI RNA Biology Initiative

Registration and Abstract Submission Now Open!

April 7, 2020

Porter Neuroscience Center, Building 35, Rooms 610/620/630

https://ncifrederick.cancer.gov/events/conferences/NCIRNAWorkshop


 

Postdoctoral Position

Structural Biology of Translation Regulation

Postdoctoral position in structural biology opens in the Korostelev lab at the University of Massachusetts Medical School: https://www.umassmed.edu/korostelev-lab/

We study translation regulation, using cryo-EM and biochemistry. We are particularly interested in: (1) Translation accuracy; (2) Ribosome’s central role in bacterial stress signaling and gene regulation; (3) Neurodegenerative and other diseases, which originate from dysregulation of translation. References to some recent publications are provided below.

Our laboratory is housed at the RNA Therapeutics Institute, a vibrant and highly interactive research community: https://www.umassmed.edu/rti/about-the-rti/faculty-members/
Our colleagues are interested in nearly all aspects of RNA biology, from small to large RNAs to RNA chemistry and therapeutics development.

We seek a highly motivated person who has recently received a PhD (or will soon receive a PhD: applications sent prior to the dissertation defense date are welcome).

Please submit
1) your CV (including publication list)
2) outline of your previous work and your scientific interests (in less than 2 pages)
3) emails of three references
to the following email address: andrei dot korostelev at umassmed dot edu

Selected publications:

  • Svidritskiy et al. “Extensive ribosome and RF2 rearrangements during translation termination”. eLife. 2019
  • Loveland et al. “Ensemble cryo-EM elucidates the mechanism of translation fidelity”. Nature. 2017
  • Demo et al. “Structure of RNA polymerase bound to ribosomal 30S subunit”. eLife. 2017
  • Abeyrathne et al. “Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome”. eLife. 2016

Tools & Services

LabCollector

Lab Data Management for RiboClub associated labs

RiboSubstrates

 Search for siRNA, SOFA-HDV, Hammerhead substrates

RASE

 Primer Design. Real-time PCR Annotation of Splicing Event

G-browse

The Generic Genome Browser

RTAnalizer

Analysis of non-autonomous retrotransposons in sequenced mammals

RNomics

Palace

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Our Mission Statement

The RiboClub was founded in 1999 by researchers at the Faculty of Medicine and Health Sciences of the Université de Sherbrooke. All the founding members have a particular interest in some aspect of RNA biology.

The RiboClub was put in place in order to :

• Establish an exceptional environment for students.
• Encourage students to interact and exchange with other students within the RiboClub.
• Stimulate interdisciplinary collaborations between groups.
• Foster the initiation of innovative projects that span multiple areas of expertise.
• Offer access to the latest technology infrastructure.
• Organize a monthly seminar series and an annual meeting.

The Université de Sherbrooke recognizes these activities and conferred us the status of “Center of Excellence in RNA Biology”. The actual research activities of the RiboClub members and associated labs include all nuances of the modern RNA field such as RNA expression, maturation (modification, cleavage and trimming, splicing), transport, and structure.

Our Mission Statement

The RiboClub was founded in 1999 by researchers at the faculty of medicine and health sciences of the Université de Sherbrooke. All the founding members have a particular interest in some aspect of RNA biology and the RiboClub was put in place in order to :

• Establish an exceptional environment for students.
• Encourage students to interact and exchange with students in other groups within the RiboClub.
• Stimulate interdisciplinary collaborations between groups.
• Foster the initiation of innovative projects that span multiple areas of expertise.
• Offer access to latest technology infrastructure.
• Organize a monthly seminar series and an annual meeting for an increased information flow.

The Université de Sherbrooke recognizes these activities and conferred us the status of “Center of Excellence in RNA Biology”. The actual research activities of the RiboClub members and associated labs include all nuances of the modern RNA field such as RNA expression, maturation (modification, cleavage and trimming, splicing), transport, the tridimensional structure and the proteins associated with RNA to form RNPs.