Postdoctoral Position
Structural Biology of Translation Regulation

Postdoctoral position in structural biology opens in the Korostelev lab at the University of Massachusetts Medical School: https://www.umassmed.edu/korostelev-lab/

We study translation regulation, using cryo-EM and biochemistry. We are particularly interested in: (1) Translation accuracy; (2) Ribosome’s central role in bacterial stress signaling and gene regulation; (3) Neurodegenerative and other diseases, which originate from dysregulation of translation. References to some recent publications are provided below.

Our laboratory is housed at the RNA Therapeutics Institute, a vibrant and highly interactive research community: https://www.umassmed.edu/rti/about-the-rti/faculty-members/
Our colleagues are interested in nearly all aspects of RNA biology, from small to large RNAs to RNA chemistry and therapeutics development.

We seek a highly motivated person who has recently received a PhD (or will soon receive a PhD: applications sent prior to the dissertation defense date are welcome).

Please submit
1) your CV (including publication list)
2) outline of your previous work and your scientific interests (in less than 2 pages)
3) emails of three references
to the following email address: andrei dot korostelev at umassmed dot edu

Selected publications:

• Svidritskiy et al. “Extensive ribosome and RF2 rearrangements during translation termination”. eLife. 2019
• Loveland et al. “Ensemble cryo-EM elucidates the mechanism of translation fidelity”. Nature. 2017
• Demo et al. “Structure of RNA polymerase bound to ribosomal 30S subunit”. eLife. 2017
• Abeyrathne et al. “Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome”. eLife. 2016